Expert Care for People Living with Neurofibromatosis. Dr. Andre Panossian has been treating patients with neurofibromatosis in the Pasadena & Glendale area for more than a decade. He recognizes the unique requirements and challenges faced by individuals with NF.
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Neurofibromatosis is a genetic condition that causes the development of tumors on virtually any nerve in the body, including the brain and spinal cord. It is usually diagnosed in childhood and can be inherited from an affected parent in approximately one-half of patients. In other words, there is roughly a 50 percent chance that an affected parent will pass on the condition. In the remainder of patients, there is no known previous family history. Currently, there are 3 types of neurofibromatosis identified. Dr. Andre Panossian has been treating patients with neurofibromatosis for more than a decade. He recognizes the unique requirements and challenges faced by individuals with NF. His primary focus is in the surgical removal of NF tumors almost anywhere on the body, including major peripheral nerves. Throughout his approach, Dr. Panossian implements a logical surgical plan that takes into account the physiology of neurofibroma tumors. He frequently meets with patients from all over the world through seminars and conferences as well as Skype. Dr. Panossian is always striving to improve surgical techniques to minimize scarring and to maintain long-term reduction of tumors.
The diagnosis of neurofibromatosis is a multi-step process that involves a thorough evaluation of clinical symptoms, family history, and various diagnostic tests:
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Dr. Andre Panossian has been treating patients with neurofibromatosis for more than a decade. He recognizes the unique requirements and challenges faced by individuals with NF. His primary focus is in the surgical removal of NF tumors almost anywhere on the body, including major peripheral nerves. Throughout his approach, Dr. Panossian implements a logical surgical plan that takes into account the physiology of neurofibroma tumors. He frequently meets with patients from all over the world through seminars and conferences as well as Skype. Dr. Panossian is always striving to improve surgical techniques to minimize scarring and to maintain long-term reduction of tumors.
Type 1 neurofibromatosis is the most common type with approximately 1 in 3000 people in the US having the condition. It is linked to a gene mutation, approximately 50 percent of individuals with the condition have no known family history.
Type 2 neurofibromatosis usually occurs within the central nervous system and the cranial nerves of the head and neck area. The main feature involves tumor formation along the 8th cranial nerve, called acoustic neuromas.
This rare condition involves tumor formation on large peripheral nerves (such as the sciatic nerve) throughout the body. It differs from NF-2 in that there are no acoustic neuromas. There are also no skin findings in most cases.
The mainstay of treatment, surgical excision is the primary intervention for neurofibromatosis. In simple terms, it involves surgically removing large tumors of the skin and underlying tissues through a traditional incision. However, there are many considerations in the treatment of individuals with neurofibromatosis. A strategy must be developed preoperatively for safe removal and for optimal results.
This newer treatment for neurofibromatosis targets the multitude of surface tumors that can occur in Type 1 NF. These tumors typically occur in patients who are in their 20's and 30's and continue to enlarge over time. They also multiply in number causing significant disfigurement in some people. Electrodesiccation is a treatment that destroys tumors of a certain size by the hundreds.
Treatment for neurofibromatosis in Pasadena & Glendale with Dr. Panossian is tailored to the individual's symptoms and may involve a combination of therapies:
Dr. Andre Panossian stands at the forefront of facial reanimation, nerve reconstruction, and complex surgical care. With specialty training in craniofacial surgery from Harvard Medical School and the Hospital for Sick Children in Toronto under the pioneering Dr. Ron Zuker, he brings unparalleled expertise to every case.
Whether you are seeking answers about your condition or exploring surgical options, Dr. Panossian can help you understand your choices and develop a personalized treatment plan tailored to your unique needs.
Dr. Andree Panossian, based in Pasadena, CA, is a skilled medical professional specializing in the treatment of Neurofibromatosis. He leads a multidisciplinary team that may include geneticists, neurologists, and oncologists to provide comprehensive care. Dr. Panossian’s approach is patient-centered, focusing on both symptom management and long-term well-being.
Neurofibromatosis is relatively rare but not exceedingly so. It affects approximately 1 in 3,000 to 4,000 individuals worldwide. The condition manifests in various forms, with Neurofibromatosis Type 1 being the most common variant. Early diagnosis and treatment are crucial for better outcomes.
Diagnosis is generally based on clinical evaluation, family history, and specific diagnostic criteria. Dr. Panossian may recommend imaging tests like MRI scans to assess the extent of nerve tissue involvement. Genetic testing can also confirm the diagnosis and guide treatment options.
The primary cause of Neurofibromatosis is genetic mutations. These mutations are often inherited but can also occur spontaneously. The mutated genes are responsible for regulating cell growth in the nervous system, and their malfunction leads to the formation of tumors.
Life expectancy can vary widely depending on the type and severity of Neurofibromatosis. While some individuals may experience a near-normal lifespan, others may face complications that could reduce life expectancy. Early diagnosis and proactive management are key to improving quality of life and longevity.
Dr. Panossian provides personalized surgical care for patients with all types of neurofibromatosis. Schedule a consultation to discuss your treatment options.
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